The Artemisia plant
Artemisia annua is an annual plant that grows to a head-high bush in summer and thrives well in Europe. It belongs to the Artemisia plant genus, which comprises approximately 250 to 500 species. Other types of Artemisia include mugwort, wormwood, rodwort or noble rhombus.
Ingredients of Artemisia annua
The Artemisia annua species is very well researched. To date, 245 different active ingredients have been isolated and detected. In addition to the best-known ingredient, artemisinin, these are e.g. numerous anti-inflammatory polyphenols. Artemisia annua has been known in Chinese folk medicine for 2000 years.
Artemisia and the Nobel Prize
The Nobel Prize is one of the highest awards in science and an honor for every researcher. In 2015 the Nobel Prize in Medicine went to Artemisia! At least indirectly ... The 84-year-old Chinese Youyou Tu received the award for her discovery of the active ingredient artemisinin in the Artemisia plant. When common malaria medications lost their effectiveness at the end of the 1960s because the malaria pathogens became increasingly resistant.
Less resistance when taking the whole plant
On the other hand, if you use the entire plant extract, resistance formation is much less likely because the plant contains 9 other substances that are effective against malaria. The malaria pathogen (a certain plasmodium) may still be able to defend itself against a single active substance (artemisinin = monosubstance) and develop resistance. However, if the pathogen is immediately confronted with a whole salvo of active ingredients, this is much more difficult for it. Unfortunately, the pharmaceutical industry works almost exclusively with mono substances. Which meant that good antimalarials are almost ineffective today. There is now a risk that this will also happen with Artemisinin.
To date, no resistance has occurred worldwide when the whole plant is used. It is therefore important to use the entire plant extract for malaria and not just a single medication. The clinical cure rate for malaria is 90-95%. However, it is important to know that there are now very resistant pathogens in some areas of Africa (e.g. Uganda) and it is therefore recommended that Artemisia therapy be continued for some time after leaving the malaria area (more on this under Dosage).
Mechanism of action of Artemisia
But how does Artemisia work against pathogens? Many mechanisms of action are still unknown, but at least one is known. And this is extremely remarkable. Artemisia annua contains a chemically stable peroxide, which according to the basic chemical rules cannot exist. Plasmodia (e.g. cancer cells) contain 10-20 times more iron ions compared to normal cells. If the peroxide comes into contact with this iron, it breaks down into two aggressive free radicals. These damage the affected cells decisively, causing them to die. This mechanism is also the reason why Artemisia should never be taken with iron, but must be taken outside of meals. Otherwise there is a risk that the peroxide bridge will break in the stomach or intestine, and not only if it is inside or near pathogens or diseased cells.
There are special varieties of Artemisia annua that, unlike wild plants, also grow well in the tropics and have an active ingredient content that is up to 20 times higher.
Artemisia annua can prevent or help with the following diseases:
- Viral infections
- Bacterial infections
- Lyme disease
- Fever / flu
- Corona navigation
- Various types of cancer
- Canker sores
- Inflammation of the brain
- Herpex simplex (herpes cold sores)
Since we assume an antibacterial, antiviral and fungicidal effect of Artemisia annua, an Artemisia cream can have an effect on various skin diseases.
Artemisia annua cream or ointment can prevent or help with the following diseases:
- Acne vulgaris
- Anal fissures
- Canker sores
- Skin infections
- Skin fungus
- Herpex simplex (cold sores)
- Itching sensation with insect bites
- Open wounds
- Rosacea on the face
Selected studies on Artemisia annua (English)
- Artemisia annua in "Nature and Healing 08/17"
- The genus Artemisia: a comprehensive review
- A Systematic Review of Anti-malarial Properties, Immunosuppressive Properties, Anti-inflammatory Properties, and Anti-cancer Properties of Artemisia Annua
- Third whole-plant Artemisia annua slows evolution of malaria drug resistance and overcomes resistance to artemisinin
- Artemisia annua dried leaf tablets treated malaria resistant to ACT and i.v. artesunate: Case reports
- First-time comparison of the in vitro antimalarial activity of Artemisia annua herbal tea and artemisinin
- Artemisinin production in Artemisia annua: studies in planta and results of a novel delivery method for treating malaria and other neglected diseases
- Evaluation and pharmacovigilance of projects promoting cultivation and local use of Artemisia annua for malaria
- Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?
- Artemisia annua as a self-reliant treatment for malaria in developing countries
- The potential of Artemisia annua L. as a locally produced remedy for malaria in the tropics: agricultural, chemical and clinical aspects
- Anti-Helicobacter pylori potential of artemisinin and its derivatives
- Antibacterial activity of some Artemisia species extract
- Artemisinin inhibits inflammatory response via regulating NF-κB and MAPK signaling pathways
- Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial
- The Antiviral Activities of Artemisinin and Artesunate
- Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV)
- Breakthrough in diabetes research: pancreatic cells produce insulin through malaria medication
- Scientists develop new cancer-killing compound from salad plant
- The Memorial Sloan Kettering Cancer Center on Artemisia annua
- Antibacterial and antioxidant activities of Artemisia annua essential oil
- Use of the whole Artemisia annua plant is more effective than just the pure active ingredient artemisinin
- Resistance to the whole plant Artemisia annua develops three times more slowly than to pure artemisinin
- Use in eye diseases (artemisinin as a potential drug for the treatment of many neurodegenerative diseases of the retina)
- Promising results in veterinary tumors of small animals
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